| Rank | Cash and due from depository institutions | Bank Name |
| 1 | $225,023,000,000 | JPMorgan Chase Bank |
| 2 | $183,259,000,000 | Citibank |
| 3 | $74,644,000,000 | Bank of America |
| 4 | $55,840,000,000 | State Street Bank and Trust Company |
| 5 | $45,354,000,000 | The Bank of New York Mellon |
| 6 | $22,324,705,000 | The Northern Trust Company |
| 7 | $15,427,000,000 | Wells Fargo Bank |
| 8 | $14,029,000,000 | Goldman Sachs Bank USA |
| 9 | $7,942,182,000 | U.S. Bank |
| 10 | $3,323,000,000 | Silicon Valley Bank |
| 11 | $677,917,000 | PNC Bank |
| 12 | $664,750,000 | East West Bank |
| 13 | $327,354,000 | Capital One |
| 14 | $270,000,000 | Comerica Bank |
| 15 | $227,684,000 | Bank Name Not Available |
| 16 | $221,947,000 | Fifth Third Bank |
| 17 | $160,171,000 | Raymond James Bank |
| 18 | $117,339,000 | BNY Mellon Trust of Delaware |
| 19 | $90,218,000 | First-Citizens Bank & Trust Company |
| 20 | $85,000,000 | Truist Bank |
| 21 | $78,461,000 | Lake Forest Bank & Trust Company |
| 22 | $61,037,000 | JPMorgan Chase Bank, Dearborn |
| 23 | $47,551,000 | Bank of Hawaii |
| 24 | $30,667,000 | Cathay Bank |
| 25 | $27,643,000 | Bank of the Orient |
| 26 | $26,473,000 | First Hawaiian Bank |
| 27 | $22,766,000 | Citicorp Trust Delaware |
| 28 | $22,298,000 | The Huntington National Bank |
| 29 | $20,349,000 | Manufacturers and Traders Trust Company |
| 30 | $9,655,000 | Bank Name Not Available |
| 31 | $8,763,000 | Santander Bank, N.A. |
| 32 | $6,456,000 | Cross River Bank |
| 33 | $6,000,000 | Banco Popular de Puerto Rico |
| 34 | $4,368,000 | Bank Name Not Available |
| 35 | $3,912,000 | 1st Financial Bank USA |
| 36 | $3,720,000 | Bank of Guam |
| 37 | $2,579,000 | FirstBank Puerto Rico |
| 38 | $2,023,000 | United Fidelity Bank, fsb |
| 39 | $379,000 | BankPacific, Ltd |
| 40 | $352,000 | Banesco USA |
| 41 | $229,000 | UMB Bank |
| 42 | $135,000 | HSBC Bank USA |
| 43 | $114,000 | Old National Bank |
| 44 | $1,000 | Amerant Bank |
| 44 | $1,000 | State Street Bank and Trust Company |
| 46 | $0 | Regions Bank |
| 46 | $0 | Wells Fargo Bank Northwest |
| 46 | $0 | BMO Harris Bank |
| 46 | $0 | KeyBank |
| 46 | $0 | Webster Bank |
| 46 | $0 | TD Bank |
| 46 | $0 | Eastern National Bank |
| 46 | $0 | Bradesco BAC Florida Bank |
| 46 | $0 | MUFG Union Bank |
| 46 | $0 | The Bank of New York Mellon Trust Company |
| 46 | $0 | Interaudi Bank |
| 46 | $0 | Habib American Bank |
| 46 | $0 | Finance Factors, Ltd. |
| 46 | $0 | Bank of America California |
| 46 | $0 | Bank Name Not Available |
| 46 | $0 | Bank Name Not Available |
| 46 | $0 | Delta National Bank and Trust Company |
| 46 | $0 | Falcon International Bank |
| 46 | $0 | Safra National Bank of New York |
| 46 | $0 | Wells Fargo National Bank West |
| 46 | $0 | American Express National Bank |
| 46 | $0 | USAA Federal Savings Bank |
| 46 | $0 | Morgan Stanley Bank |
| 46 | $0 | Charles Schwab Premier Bank, SSB |
| 46 | $0 | The Bank of East Asia Ltd. |
| 46 | $0 | Bank of India |
| 46 | $0 | Industrial Bank of Korea |
| 46 | $0 | Bank of China |
| 46 | $0 | Metropolitan Bank and Trust Company |
| 46 | $0 | Mizrahi Tefahot Bank, Ltd. |
| 46 | $0 | State Bank of India |
| 46 | $0 | Bank of Baroda |
| 46 | $0 | State Bank of India |
| 46 | $0 | Allied Irish Banks |
| 46 | $0 | Bank Hapoalim B.M. |
| 46 | $0 | BANCO BILBAO VIZCAYA, S.A. |
| 46 | $0 | STANDARD CHARTERED BANK, PLC |
| 46 | $0 | MashreqBank, PSC |
| 46 | $0 | Morgan Stanley Private Bank |
| 46 | $0 | USAA Savings Bank |
| 46 | $0 | WEX Bank |
| 46 | $0 | Bank of the West |
| 46 | $0 | Wells Fargo Bank South Central |
| 46 | $0 | Discover Bank |
| 46 | $0 | U. S. Century Bank |
| 46 | $0 | Charles Schwab Bank, SSB |
| 46 | $0 | Ally Bank |
| 46 | $0 | Citizens Bank |
| 46 | $0 | Bank Name Not Available |
| 46 | $0 | First Republic Bank |
| 46 | $0 | Charles Schwab Trust Bank |
| 46 | $0 | BNY Mellon |
| 98 | $-1,000 | City National Bank |
| 98 | $-1,000 | Bank Name Not Available |
